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Key:
NRTI - nucleoside/nucleotide reverse transcriptase inhibitors (nukes)

NNRTI - non-nucleoside/nucleotide reverse transcriptase inhibitors (non-nukes)

PI - protease inhibitor

EI - entry inhibitor

FI - fusion inhibitor

CCR5 - chemokine co-receptor 5 (chemokine receptor which HIV uses as a coreceptor to gain entry into macrophages)

INI - intergrase inhibitor

HIV Drugs By Manufacturer

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Common Name Generic name/abbreviations Trade Name Class
 
GlaxoSmithKline (GSK)
AZT, ZDV zidovudine Retrovir NRTI
3TC lamuvidine Epvir NRTI
AZT + 3TC zidovudine+lamuvidine Combivir NRTI
ABC abacavir Ziagen NRTI
AZT+3TC+abacavir zidovudine+lamivudine+abacavir Trizivir NRTI
abacavir + 3TC abacavir+lamuvidine Kivexa NRTI
FPV fosamprenavir Telzvir PI
 
Pipeline Drugs
IDX899     NNRTI (Phase1/ 2)
GSK364735     INI(Phase 1)
 
Bristol-Myers Squibb (BMS)
ddI didanosine Videx NRTI
d4T stavudine Zerit NRTI
EFV efavirenz Sustiva (EU) NNRTI
ATV atazanavir Reyataz PI
Atripla (with Gilead) efavirenz+FTC+tenofovir Atriprila NNRTI+2NRTIs
 
Gilead Sciences
TDF tenofovir Viread NRTI
FTC emtricitabine Emtriva NRTI
Tenofovir+ FTC emtricitabine+tenofovir Truvada NRTI
Atripla (with BMS) efavirenz+FTC+tenofovir Atriprila NNRTI+2NRTIs
 
Pipeline Drugs
elvitegravir     INI (Phase 3)
 
Tibotec
ETR etravirine Intelence NNRTI
DRV darunivir Prezista PI
 
Pipeline Drugs
TMC278 rilpvirine   NNRTI (Phase 3)
 
Abbott
RTV ritonavir Norvir PI
LPV lopinavir+ritonavir Kaletra+Aluvia PI
 
Pfizer
DLV delavirdine Rescriptor NNRTI
NFV nelfinavir Viracept PI
MVC maraviroc Celsentri
(Selzentry)
EI
 
Pipeline Drugs
UK 543,061     NNRTI (Phase 1)
 
Boehringer
NVP nevirapine Viramune NNRTI
TPV tipranavir Aptivus PI
       
Pipeline Drugs
BILR 355     NNRTI (Phase 2)
 
Roche
SQV saquinavir Invirase PI
T-20 enfuvirtide Fuzeon FI
       
Merck
IDV indinavir Crixivan PI
RGV raltegravir Isentress INI
 
Schering
Pipeline Drugs
Vicriviroc VCV   EI (CCR5) (Phase 3)

Co-infections

Hepatatis C

Drugs that are used in combination:

Schering Plough:

Roche:

Pipeline Drugs/Clinical trials: information can be found at:

http://www.hcvadvocate.org/hepatitis/hepC/HCVDrugs.html

http://www.treatmentactiongroup.org

TB Drugs:

1st line drugs: Generic drugs

2nd line drugs: (SLDs)

There are six classes of SLDs used for the treatment of TB. A drug may be classed as second-line instead of first-line for one of two possible reasons: it may be less effective than the first-line drugs (e.g., p-aminosalicylic acid); or, it may have toxic side-effects (e.g., cycloserine); or it may be unavailable in many developing countries (e.g., fluoroquinolones):

Other drugs that may be useful, but are not on the World Health Organisation (WHO) list of SLDs:

These drugs may be considered "third-line drugs" and are either because they are not very effective (e.g., clarithromycin) or because their efficacy has not been proven (e.g., linezolid, R207910). Rifabutin is effective, but is not included on the WHO list because for most developing countries, it is impractically expensive.

Pipeline Drugs/Clinical trials: information can be found at:
http://www.treatmentactiongroup.org

This is a peer-led network. Information on this website is provided as a guide only.
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