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Koronis Update - Setback

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Ben Cromarty
Member
Posts: 451
Koronis Update - Setback
Posted on: July 3 2008, 08:50 am

Koronis has been working on a new drug called KP-1461, which is supposed to work by speeding up the mutation rate of HIV. In theory, this would lead HIV to mutate so much that it becomes unable to infect cells and replicate. This approach, called terminal mutagenesis, was supported by lab experiments which showed that when HIV was exposed to KP-1461 it eventually mutated itself to death.

Recent results, however, have shown no anti-HIV activity. Full details: http://www.thebody.com/content/art47195.html?mtrk=8840621

Koronis is committed to understanding these discordant results and will attempt to validate the original 2002 research on KP-1461.
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