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TAILoR - Telmisartan and Insulin Resistance in HIV study is recruiting

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UK CAB Moderator
Global Moderator
Posts: 826
TAILoR - Telmisartan and Insulin Resistance in HIV study is recruiting
Posted on: March 14 2014, 11:48 am

See information below for the TAILoR study for those you may wish to participate.  See list below for recruitment centres across the UK. The website http://www.tailortrial.org.uk  has more information.
Thanks, Memory

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TAILoR is a clinical trial designed to determine the effect of telmisartan on insulin resistance in HIV positive patients on combination anti-retroviral therapy.

This trial is co-sponsored by the University of Liverpool and the Royal Liverpool and Broadgreen NHS Hospital Trust, funded by the National Institute for Health Research - Efficacy and Mechanism Evaluation Programme (NIHR-EME), and coordinated  by the Clinical Trials Research Centre at the University of Liverpool.

TAILoR is a UK wide study with sites across England. Please see the list of recruiting centres for more information

The first TAILoR participant was recruited in March 2012. We now have 93 patients recruited across 11 open sites.

Currently open sites and their Principal Investigators:
Site                                                            Principal Investigator
Royal Liverpool Hospital, Merseyside                Prof. Saye Khoo
Royal Free Hospital, London                             Prof. Margaret Johnson
Guys and St Thomas' Hospital, London            Dr. Barry Peters
Kings College Hospital, London                         Dr. Frank Post
Royal Bournemouth Hospital, Dorset                 Dr. Elbushra Herieka
Western General Hospital, Edinbugh                  Prof Clifford Leen
St. James' Hospital, Leeds                                   Dr Jane Minton
City of Coventry Health Centre, Coventry           Dr Satyajit Das
Brighton and Sussex University Hospitals           Dr. Duncan Churchill
James Cook University Hospital, Middlesbrough    Dr David Chadwick
YorClinic, York                                                   Dr Fabiola Martin

Summary information about he trial can be found here:
http://www.tailortrial.org.uk/summary.html
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Simon Collins
Global Moderator
Posts: 651
Re: TAILoR - Telmisartan and Insulin Resistance in HIV study is recruiting
Reply #1 on: March 17 2014, 09:17 am

Thanks - I think this is an interesting study.

On the plus side there may be cardiovascular benefits from enrolling.

It is also one of the few studies looking at an intervention for fat accumulation (though it is far from clear whether this will have any effect on this).

Also, one of the few cautions from using telmisartin is low blood pressure and people at highest risk for this are already excluded from entering the study.

I am on the SC of this study and they need help with enrolment.
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